Status:
COMPLETED
Intracranial Atherosclerosis and Depression After Coronary Artery Bypass Graft
Lead Sponsor:
Yale University
Conditions:
Depression
Intracranial Atherosclerosis
Eligibility:
All Genders
40+ years
Brief Summary
The purpose of the study is to examine if blood flow in the brain before coronary artery bypass graft surgery has an effect on depression after surgery. The main hypothesis of the study states that p...
Eligibility Criteria
Inclusion
- Age: 40 years or older
- Will be having CABG surgery at the Yale New Haven Hospital
- Be able to provide informed consent
- Have a household telephone
- A fluent English speaker, and possessing no communication barrier
- Be able to come to the study site or to have the study team come to his/her home.
- Has a family member or partner/ friend who could provide collateral information
Exclusion
- Has had previous CABG surgery
- History of dementia diagnosis or cognitive impairment (CDR \>/= 1)
- Auditory or visual impairment that would interfere with study procedures
- Active alcohol or substance abuse problem based CAGE-AID (endorsing two or more items)
- History of Bipolar Disorder, Schizophrenia, Schizoaffective Disorder, or any Psychotic Disorder by medical history or self-report.
- Presence of non-cardiovascular conditions likely to be fatal within 1 year
Key Trial Info
Start Date :
September 1 2012
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
Estimated Enrollment :
169 Patients enrolled
Trial Details
Trial ID
NCT01838356
Start Date
September 1 2012
Last Update
January 17 2018
Active Locations (2)
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1
Yale University School of Medicine
New Haven, Connecticut, United States, 06510
2
The Johns Hopkins University
Baltimore, Maryland, United States, 21218