Status:
COMPLETED
Is Non-Cardiac Chest Pain Caused by Sustained Longitudinal Smooth Muscle Contraction?
Lead Sponsor:
Queen's University
Conditions:
Chest Pain Atypical Syndrome
Eligibility:
All Genders
18-75 years
Brief Summary
Non-cardiac chest pain (NCCP) is a common disorder whose pathophysiology is poorly understood. Some evidence suggests it may be related to sustained esophageal contractions (SECs) of longitudinal smoo...
Eligibility Criteria
Inclusion
- Healthy volunteers:
- free of esophageal symptoms
- not on any acid suppressing medications
- Non Cardiac Chest Pain Patients:
- Angina like chest pain occuring at least once per month
- Coronary artery disease ruled out by stress test or angiogram
Exclusion
- pre existing motility disorder of the esophagus
- connective tissue disease
- pregnancy
- taking calcium channel blockers, Nitrates, Gabapentin, Narcotics, Tricyclic antidepressants, Anti seizure medications
Key Trial Info
Start Date :
October 1 2013
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
October 1 2014
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT01839058
Start Date
October 1 2013
End Date
October 1 2014
Last Update
November 26 2018
Active Locations (1)
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1
Hotel Dieu Hospital
Kingston, Ontario, Canada, K7L 5G2