Status:

COMPLETED

Assessment of Helical Tomotherapy Radiotherapy (54 Gy) Followed by Surgery in Retro-peritoneal Liposarcoma

Lead Sponsor:

Institut Bergonié

Conditions:

Liposarcoma

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Retro peritoneal liposarcomas are rare (less than 15% of sarcomas) whose prognosis is locoregional. In the treatment of retroperitoneal liposarcomas main prognostic factor is the quality of the surgi...

Detailed Description

Retro peritoneal liposarcomas are rare (less than 15% of sarcomas) whose prognosis is locoregional. In the treatment of retroperitoneal liposarcomas main prognostic factor is the quality of the surgic...

Eligibility Criteria

Inclusion

  • Liposarcoma histologically proven, in case of non-contributive biopsy: diagnosis radiologically validated within a multidisciplinary meeting
  • Protocol TOMOREP technically feasible,
  • Patients over 18 years
  • Considered as resectable even if multi-visceral excision is needed
  • Absence of morbidity contra-indicating surgery. The evaluation will be performed by the surgeon or the radiotherapist according to the definitions by the ASA classification.
  • Original form (as well as tumors made after first incomplete excision) and form in first relapse.
  • Life expectancy greater than 6 months
  • Patient signed informed consent,
  • Patient affiliated to a social security.

Exclusion

  • Metastasis associated
  • Extension intraperitoneal associated, mesenteric extension
  • bilaterally
  • Against disease-indicating the need for surgery (ASA 3 and 4).
  • Contra-indication to radiotherapy (such as prior radiotherapy into the volume to treat).
  • Patient included in another clinical trial
  • Patient unable to undergo medical monitoring test for any geographical, social or psychological reasons,
  • Private patient freedom and major subject of a measure of legal protection or unable to consent.

Key Trial Info

Start Date :

January 20 2009

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 19 2018

Estimated Enrollment :

48 Patients enrolled

Trial Details

Trial ID

NCT01841047

Start Date

January 20 2009

End Date

December 19 2018

Last Update

September 3 2025

Active Locations (5)

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Page 1 of 2 (5 locations)

1

Centre Paul Strauss

Strasbourg, Alsace, France, 67000

2

Institut Bergonié

Bordeaux, Aquitaine, France, 33000

3

Centre Claudius Regaud

Toulouse, Midi-Pyrénées, France, 31000

4

Centre René Gauducheau

Nantes, Pays de la Loire Region, France, 44000