Status:
COMPLETED
Serum Biomarker of Plaque Vulnerability and Contrast Ultrasound of Carotid Artery
Lead Sponsor:
Kyunghee University Medical Center
Conditions:
Intraplaque Neovascularization Evaluated by Carotid Enhanced Ultrasound Well Reflect the Plaque Vulnerability
Eligibility:
All Genders
Brief Summary
No serum biomarker has qualified for clinical use until now. However several biomarkers, especially markers of inflammatory or proteolytic activity seem to promising in the identification of vulnerabl...
Eligibility Criteria
Inclusion
- patients with carotid plaques size more than 2mm by carotid ultrasound
Exclusion
- known allergy to albumin, or to the ultrasound contrast agent
- the patients with history of carotid endarterectomy and carotid stent
- acute myocardial infarction, cardiogenic shock
- connective tissue disease and malignancy
- creatinine clearance lower than 30ml/min and the history of dialysis
Key Trial Info
Start Date :
May 1 2010
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2013
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT01842490
Start Date
May 1 2010
End Date
December 1 2013
Last Update
August 25 2014
Active Locations (1)
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1
Division of Cardiology, Department of Internal Medicine, Kyung Hee University School of Medicine
Seoul, Seoul, South Korea, 130-872