Status:

COMPLETED

Vaginal Estrogen With Pessary Treatment

Lead Sponsor:

London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

Collaborating Sponsors:

Academic Medical Organization of Southwestern Ontario

University of Western Ontario, Canada

Conditions:

Vaginal Infection

Urinary Tract Infection

Eligibility:

FEMALE

18-100 years

Phase:

NA

Brief Summary

Patients presenting with pelvic organ prolapse will be offered the use of a pessary. Vaginal estrogen cream treatment with the pessary will be randomized amongst the patients and patient satisfaction ...

Detailed Description

This will be a double-blinded, placebo-controlled, randomized controlled trial. Eligible patients presenting to the urogynaecology clinic with pelvic organ prolapse will be offered management with a p...

Eligibility Criteria

Inclusion

  • Any patient presenting to the clinic with pelvic organ prolapse will be offered management with a pessary and will be offered participation in the study.

Exclusion

  • have a contraindication to the use of estrogen cream or products
  • have any allergy to the use of estrogen cream or products
  • have a past medical or family history of breast cancer
  • have a past medical history of thromboembolism, myocardial infarction and stroke or are pregnant
  • have previously used Premarin vaginal cream
  • are currently using oral estrogen
  • are not competent to consent

Key Trial Info

Start Date :

July 1 2012

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 1 2016

Estimated Enrollment :

150 Patients enrolled

Trial Details

Trial ID

NCT01843166

Start Date

July 1 2012

End Date

December 1 2016

Last Update

November 6 2018

Active Locations (1)

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London Health Sciences Centre, University of Western Ontario

London, Ontario, Canada, N6A 5W9