Status:

COMPLETED

Acupuncture to Improve Comfort of Children on a Ventilator in the Intensive Care Unit

Lead Sponsor:

Seattle Children's Hospital

Conditions:

Agitation

Eligibility:

All Genders

6-17 years

Phase:

NA

Brief Summary

The purpose of this study is to determine whether acupuncture is effective at improving comfort in children on a ventilator in the intensive care unit. Our hypothesis is that the patients receiving ac...

Detailed Description

Rationale: Use of narcotics and benzodiazepines is common in the pediatric intensive care unit (PICU) to alleviate pain and anxiety, especially for patients who are mechanically ventilated. Pain contr...

Eligibility Criteria

Inclusion

  • age ≥6 months to \<18 years
  • intubated and mechanically ventilated
  • patient requires pharmacologic sedation/analgesia to tolerate mechanical ventilation
  • ≤72 hours of mechanical ventilation at time of enrollment with anticipated need of mechanical ventilation for at least ≥48 hours more (in order to be able to receive at least one acupuncture session)
  • approval of treating physician

Exclusion

  • underlying neurologic condition that could impact sedation/analgesia needs
  • coagulopathy (inr ≥ 1.8) or history of spontaneous bruising
  • thrombocytopenia (platelets \<20,000 that has not been treated with a platelet transfusion)
  • hemodynamic instability (on continuous infusion of vasopressor or inotrope)
  • sepsis or bacteremia on antibiotic therapy \<24 hours
  • severe generalized skin disorder (e.g., epidermolysis bullosa, Stevens-Johnson)
  • ward of state
  • being treated with therapeutic level of systemic anticoagulation (e.g., heparin with unfractionated heparin activity level ≥0.3, enoxaparin with low molecular weight heparin activity level ≥0.5, warfarin with inr ≥1.8)
  • immunosuppressed (on chemotherapy {e.g., daunorubicin, vincristine}, immunosuppressive medications {e.g., sirolimus, tacrolimus, cyclosporine, mycophenolate mofetil, high dose steroids \>4mg/kg/day}, or immunosuppressive biologics {e.g., thymoglobulin, etanercept, infliximab, adalimumab, rituximab})

Key Trial Info

Start Date :

March 1 2013

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 1 2016

Estimated Enrollment :

17 Patients enrolled

Trial Details

Trial ID

NCT01848158

Start Date

March 1 2013

End Date

June 1 2016

Last Update

August 13 2020

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Seattle Children's Hospital

Seattle, Washington, United States, 98105