Status:

COMPLETED

Deceased Donor Biomarkers and Recipient Outcomes

Lead Sponsor:

Yale University

Collaborating Sponsors:

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Johns Hopkins University

Conditions:

Deceased Donor Kidney Transplant

Acute Kidney Injury

Eligibility:

All Genders

Brief Summary

Compared to chronic dialysis, kidney transplantation provides recipients with longer survival and better quality of life at a lower cost. In order to meet increasing demands for kidney allografts, kid...

Detailed Description

Our study has several key processes that we have developed and tested to address our scientific aims: 1. Enrollment We will collect urine samples from approximately 1600 deceased donors and appro...

Eligibility Criteria

Inclusion

  • Donor Cohort: Appropriate informed consent for research according to OPO policies
  • Recipient Cohorts: Any recipient of at least one kidney from a deceased donor enrolled by our participating OPOs

Exclusion

  • • Donor Cohort: Lack of adequate biospecimen quantity or quality as per protocol

Key Trial Info

Start Date :

May 1 2010

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

March 1 2020

Estimated Enrollment :

1679 Patients enrolled

Trial Details

Trial ID

NCT01848249

Start Date

May 1 2010

End Date

March 1 2020

Last Update

April 9 2020

Active Locations (17)

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Page 1 of 5 (17 locations)

1

Yale New Haven Hospital

New Haven, Connecticut, United States, 06510

2

University of Maryland Medical Center

Baltimore, Maryland, United States, 21201

3

New England Organ Bank

Waltham, Massachusetts, United States, 02451

4

Gift of Life Michigan

Ann Arbor, Michigan, United States, 48108