Status:
UNKNOWN
Cardiopulmonary Capacity in Elderly With Different Ranges of Serum Thyroid Stimulating Hormone
Lead Sponsor:
Universidade Federal do Rio de Janeiro
Collaborating Sponsors:
Conselho Nacional de Desenvolvimento Científico e Tecnológico
Conditions:
Healthy
Eligibility:
All Genders
65+ years
Phase:
PHASE4
Brief Summary
The purpose of this study is to correlate in an elderly population (≥ 65 years), the different levels of serum TSH, with cardiopulmonary capacity, quality of life, depressive symptoms and cognition. A...
Detailed Description
Specific Objectives: Describe the cardiopulmonary capacity in elderly people with 65 years old or more, in different quartiles of normal range for serum TSH. Assess the quality of life, mini mental ...
Eligibility Criteria
Inclusion
- Age ≥ 65 years.
- Healthy Men and women
- Registration at the University Hospital Clementino Fraga Filho (HUCFF).
Exclusion
- Hypothalamic-pituitary disease
- Congestive cardiac insufficiency, chronic renal failure, acute renal failure, stroke, chronic obstructive pulmonary disease, asthma, cancer and / or cirrhosis.
- Diseases of the aorta, peripheral vascular disease, coronary artery disease (including angina, history of prior myocardial infarction or angina, or history of cardiac catheterization and angioplasty).
- Use of corticosteroids, amiodarone or dopamine, as well as any drug that interferes with the levels of thyroid hormones and / or thyroid function.
- Use of drugs that interfere with autonomic adaptation mechanism, such as beta-blockers, prolopa and calcium channel blockers. Hypertensive patients without use of such drugs may be included.
- Patients bedridden, wheelchair or with physical limitations (joint and muscle) to prevent the standing position for at least 20 minutes and the realization of the cardiopulmonary exercise test.
- Obesity with a body mass index equal or greater than 35 kg/m2.
Key Trial Info
Start Date :
September 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 1 2014
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT01849861
Start Date
September 1 2011
End Date
September 1 2014
Last Update
May 13 2013
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Universidade Federal do Rio de Janeiro
Rio de Janeiro, Rio de Janeiro, Brazil, 21941-590