Status:

COMPLETED

UNGF Assessment in Patients With Detrusor Overactivity Undergoing Sacral Neuromodulation

Lead Sponsor:

Northwell Health

Collaborating Sponsors:

Medtronics, Inc.

Conditions:

Detrusor Overactivity

Eligibility:

FEMALE

18+ years

Brief Summary

The purpose of this study is to find a noninvasive test to help physicians diagnose detrusor overactivity (DO), to use this urine test to help diagnose bladder problems, determine if treatments are wo...

Eligibility Criteria

Inclusion

  • for controls: age greater than or equal to 18; female gender, ability to provide informed consent and complete study requirements; subject has to be without urinary symptoms
  • for cases: age greater than or equal to 18; female gender; ability to provide informed consent and complete study requirements; the subject should have symptoms of detrusor overactivity, including urinary frequency, urgency, or urge incontinence, for greater than or equal to 3 months; urodynamic diagnosis of detrusor overactivity; failed treatment with behavioral modification and anticholinergic medication

Exclusion

  • active urinary tract infection; currently undergoing hemodialysis or has severe renal impairment; bladder tumors; uncontrolled diabetes mellitus; post void residual greater than 100ml; history of use of anticholinergic treatment within past 21 days; history of urinary tract operation within 6 months prior to screening; heart failure; uncontrolled hypertension; severe neurological disease; history of botox usage within 1 year

Key Trial Info

Start Date :

August 1 2011

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

March 1 2016

Estimated Enrollment :

50 Patients enrolled

Trial Details

Trial ID

NCT01850706

Start Date

August 1 2011

End Date

March 1 2016

Last Update

October 26 2016

Active Locations (1)

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North Shore University Hospital

Manhasset, New York, United States, 11030