Status:
COMPLETED
Comparison Between Two Different Antibiotic Regimens for the Placement of Dental Implants
Lead Sponsor:
Université de Montréal
Conditions:
Dental Implants
Eligibility:
All Genders
35-75 years
Phase:
PHASE1
Brief Summary
In order to prevent infections and complications, it has been initially established with the dental implant placement protocol that pre- and post-operative antibiotics should be prescribed to the pati...
Detailed Description
Introduction After the discovery of penicillin as an antimicrobial agent in 1928, and later methicillin, an important improvement of the prognosis of antimicrobial therapies occurred. However, an inc...
Eligibility Criteria
Inclusion
- Subjects more than 34 years old and less than 76 years old.
- Periodontally healthy remaining dentition or presenting with mild gingivitis with adequate oral hygiene.
- Presence of a partially edentulous alveolar ridge that is planned to be restored with no more than 2 implants.
- Presence of a non-infected site.
- Presence of enough bone and soft tissue for the implant to be placed without additional bone augmentation in a 1-stage approach (with healing abutment).
- Implants 8mm long or longer.
- Subjects able and willing to provide written informed consent and comply with study procedures.
Exclusion
- Subjects taking regular analgesics or antidepressants.
- Smoking 10 cigarettes/cigars or more per day.
- Drug abuse.
- Completely edentulous individuals.
- Pregnant and nursing women.
- Allergies to amoxicillin and/or non-steroidal anti-inflammatory analgesics.
- Any systemic or local immunodeficiency.
- Any blood coagulation impairment.
- Presence of uncontrolled periodontitis or poor oral hygiene.
- Presence of any acute oral infection.
- Presence of uncontrolled diabetes or other systemic diseases.
- Previous radiation therapy in the head and neck area.
- Intravenous bisphosphonates.
- Oral bisphosphonates intake for more than 3 years.
- Long-term intake of corticosteroids.
- Need for routine prophylactic antibiotics prior dental surgery.
Key Trial Info
Start Date :
July 1 2014
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2017
Estimated Enrollment :
42 Patients enrolled
Trial Details
Trial ID
NCT01851681
Start Date
July 1 2014
End Date
May 1 2017
Last Update
May 4 2017
Active Locations (1)
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1
Université de Montréal - Faculty of Dentistry - Dental clinics
Montreal, Quebec, Canada, H3T 1J4