Status:
COMPLETED
Implant Surface Decontamination With 2 % Chlorhexidine in Peri-implantitis Treatment
Lead Sponsor:
University Medical Center Groningen
Conditions:
Periodontal Diseases
Peri-implantitis
Eligibility:
All Genders
Phase:
NA
Brief Summary
Peri-implantitis is a infectious disease that resides in the mucosa surrounding dental implants and also affects the supporting bone. Because the number of implants placed in everyday clinical practic...
Eligibility Criteria
Inclusion
- The patient is at least 18 years of age;
- The patient has at least one endosseous implant in the oral cavity with clinical and radiographical signs of peri-implantitis. Peri-implantitis is defined as a loss of marginal bone more than or equal to 2 mm as compared to a fixed reference point on the dental implant, in combination with bleeding and/or suppuration on probing and a peri-implant probing depth more than or equal to 5 mm;
- The implants have been exposed to the oral environment for at least two years;
- The patient is capable of understanding and giving informed consent.
Exclusion
- Medical and general contraindications for the surgical procedures;
- A history of local radiotherapy to the head and neck region;
- Pregnancy and lactation;
- Insulin dependent diabetes;
- Systemic use of antibiotics during the last 2 months;
- Long-term use of anti-inflammatory drugs;
- Incapability of performing basal oral hygiene measures as a result of physical or mental disorders;
- Active, uncontrolled periodontal pathology of the remaining dentition;
- Local use of antibiotics or use of other anti-septic / antimicrobial therapies in the oral cavity during the last 2 months;
- Bruxism;
- Implants placed in skin grafted areas;
- Implants with bone loss due to other reasons than bacterial infection (e.g. loose screw, inadequate positioning of the implant);
- Implants with bone loss exceeding 2/3 of the length of the implant or implants with bone loss beyond the transverse openings in hollow implants;
- Implant mobility;
- Implants at which no position can be identified where proper probing measurements can be performed;
- Previous surgical treatment of the peri-implantitis lesions;
- Previous non-surgical treatment of the peri-implantitis lesions during the last 6 months (scaling or curettage).
Key Trial Info
Start Date :
March 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 1 2013
Estimated Enrollment :
44 Patients enrolled
Trial Details
Trial ID
NCT01852253
Start Date
March 1 2010
End Date
April 1 2013
Last Update
April 19 2024
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
University Medical Center Groningen
Groningen, Netherlands, 9713 AV