Status:
COMPLETED
Effects of Growth Hormone Administration on Muscle Strength and Body Composition in Men Over 50 Years Old
Lead Sponsor:
Universidade Federal do Rio de Janeiro
Conditions:
Healthy
Eligibility:
MALE
50-70 years
Phase:
PHASE4
Brief Summary
The growth hormone (GH) secretion declines gradually with age, with studies demonstrating a progressive reduction of 14% secretion per decade of life beginning in the second decade. Other studies sugg...
Detailed Description
At baseline, subjects are submitted to evaluation of GH secretion, testosterone level, body composition, and muscle strength. Absence of GHD and normal testosterone levels were necessary for the inclu...
Eligibility Criteria
Inclusion
- Healthy and non-sedentary men aged 50-70 years
Exclusion
- pituitary disease, GH use in the last 12 months, severe acute disease, hepatic and/or renal chronic disease, uncontrolled systemic arterial hypertension, diabetes mellitus, psychiatric disorders, history of cancer, non-treated hypogonadism and the presence of any other disease that could interfere with the somatotrophic axis.
Key Trial Info
Start Date :
January 1 2012
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2013
Estimated Enrollment :
13 Patients enrolled
Trial Details
Trial ID
NCT01853566
Start Date
January 1 2012
End Date
June 1 2013
Last Update
September 3 2014
Active Locations (1)
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1
Hospital Universitário Clementino Fraga Filho - UFRJ
Rio de Janeiro, Rio de Janeiro, Brazil, 21941-913