Status:
COMPLETED
Benefit of Pharyngeal and Oesophageal pH-impedance of Patients With High Suspicion of Laryngopharyngeal Reflux
Lead Sponsor:
University Hospital, Bordeaux
Conditions:
Laryngopharyngeal Reflux
Oesophageal pH-impedance
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
Laryngopharyngeal reflux (LPR) is the retrograde movement of gastric contents into the larynx, pharynx and upper aerodigestive tract. The symptoms and manifestations are very changeable and non specif...
Detailed Description
This is a monocentric, prospective descriptive study. Patients will be recruited in otolaryngology and gastroenterology departments of Bordeaux teaching hospital. A first clinical, endoscopic and pH-i...
Eligibility Criteria
Inclusion
- age : 18 to 80 years old.
- Written consent
- Laryngopharyngeal symptoms (dysphonia, and/or globus and/or sensation, and/or pharyngeal pain, and/or cough) for 3 months at least.
- No PPI for at least 15 days
- Social security affiliation
Exclusion
- Sinusitis or chronic rhinitis (in the previous year)
- Laryngeal trauma, tracheotomy or pharyngolaryngeal surgery
- pregnancy or absence of efficacy contraception
- breast feeding
- history of gastrointestinal pathology, diabetes, neurological condition
- cardio-vascular history requiring the taking of Plavix
- esomeprazole contraindication or intolerance
Key Trial Info
Start Date :
May 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
July 1 2015
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT01854970
Start Date
May 1 2013
End Date
July 1 2015
Last Update
July 23 2015
Active Locations (1)
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1
CHU de Bordeaux
Bordeaux, France, 33000