Status:
COMPLETED
Vitamin D3, Folic Acid and Fexofenadine in Healthy Volunteers
Lead Sponsor:
University of Zurich
Conditions:
Physiological Effects of Vitamin D
Eligibility:
All Genders
18-65 years
Phase:
PHASE1
Brief Summary
The study is conducted to assess the effect of a vitamin D3 supplementation on the activities of two intestinal transporters and on the pharmacokinetics of the transporter substrates folic acid and fe...
Eligibility Criteria
Inclusion
- Inclusion criteria:
- male or female
- age 18 to 65 years at study entry
- signed informed consent form
- Body Mass Index \> 18 - \< 30 kg/m2
- Participants must not have any other diseases (as assessed by the screening examination)
- Participants must not take any concomitant medications except oral contraceptives in females
- Normal blood count
- Exclusion criteria:
- Subjects with confirmed or suspected hypersensitivity towards the study medications
- Contemporaneous participation in any other study
- Females only: pregnancy
- Females only: breast-feeding
- Clinically significant abnormal laboratory findings
- Known or suspected present or past malignancies of any kind
- Known or suspected active infections, serious infections in the preceding 3 months
- Positive hepatitis B, hepatitis C and / or HIV 1/2 serology
- Subjects known or suspected not to comply with the study regulations
- Subjects employed at the participating departments of the University Hospital Zürich.
- Known or suspected present or past diseases which may interfere with the study
- smokers
- alcohol or drug abuse
Exclusion
Key Trial Info
Start Date :
May 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 1 2013
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT01856348
Start Date
May 1 2013
End Date
July 1 2013
Last Update
August 13 2013
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
University Hospital Zurich, Dept. of Clinical Pharmacology and Toxicology
Zurich, Canton of Zurich, Switzerland, 8091