Status:

COMPLETED

Safety and Pharmacokinetics Study of DU-176b Administered to Non-valvular Atrial Fibrillation With Severe Renal Impairment

Lead Sponsor:

Daiichi Sankyo Co., Ltd.

Conditions:

Non-valvular Atrial Fibrillation

Eligibility:

All Genders

20+ years

Phase:

PHASE3

Brief Summary

To assess the safety and pharmacokinetics of DU-176b administered to non-valvular atrial fibrillation patients with severe renal impairment, compared with DU-176b administered to non-valvular atrial f...

Eligibility Criteria

Inclusion

  • Patients with NVAF and SRI, or patients with NVAF and Normal/MiRI.

Exclusion

  • Patients who are on hemodialysis or patients who may start hemodialysis before the follow-up assessment
  • Patients who are at a significantly high risk for bleeding
  • Patients who are receiving treatment with any anticoagulant drugs excluding warfarin, rivaroxaban, and dabigatran
  • Patients who have evidence of hepatic function test abnormalities

Key Trial Info

Start Date :

November 1 2011

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 1 2013

Estimated Enrollment :

93 Patients enrolled

Trial Details

Trial ID

NCT01857622

Start Date

November 1 2011

End Date

January 1 2013

Last Update

March 5 2019

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Tokyo Women's Medical University Hospital

Tokyo, Japan, 162-0054