Status:
COMPLETED
Drug Interaction Between Irbesartan and Hydrochlorothiazide
Lead Sponsor:
Damanhour University
Conditions:
Healthy
Eligibility:
MALE
18-45 years
Phase:
NA
Brief Summary
This study was conducted to investigate any potential reaction between irbesartan and hydrochlorothiazide.
Eligibility Criteria
Inclusion
- At least 18 years old and not more than 45 healthy normotensive male volunteers Who had passed all the screening parameters
Exclusion
- A clinically significant abnormal physical exam, medical history, or laboratory studies If they showed a sitting SBP of \>140 or \<100 mmHg, DBP \> 90 or \<60mm Hg, or a pulse rate of \> 95 or \< 50 beats/min at screening The use of any prescription drug within the previous month or use of any over-the-counter medication within the past 14 days A history of blood dyscrasias A history of alcohol or drug abuse within the past year Donation of blood during the 8 weeks prior to the study or plans to donate blood during or within 8 weeks of completing the study Unable to tolerate vein puncture and multiple blood samplings Any surgical/medical condition that might alter drug absorption, distribution, metabolism, or excretion
Key Trial Info
Start Date :
March 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 1 2013
Estimated Enrollment :
18 Patients enrolled
Trial Details
Trial ID
NCT01858610
Start Date
March 1 2013
End Date
April 1 2013
Last Update
May 27 2013
Active Locations (1)
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1
Pharmaceutics Department, Faculty of Pharmacy, Damanhour University
Damanhur, Egypt