Status:

COMPLETED

Anti-Tumor Necrosis Factor (TNF) Treatments, Work Productivity and Quality of Life in Crohn's Disease

Lead Sponsor:

AbbVie

Conditions:

Crohn's Disease

Eligibility:

All Genders

18-65 years

Brief Summary

This multicenter, prospective, post marketing observational study (PMOS) was designed to demonstrate long-term effects of anti-Tumor Necrosis Factor therapies on Work Productivity and Impairment scale...

Detailed Description

Male or female participants between 18 - 65 years of age with moderate to severe CD for whom the treating physician had recently initiated an anti-TNF treatment were included in this study. Anti-TNF t...

Eligibility Criteria

Inclusion

  • Male or female participants between 18-65 years of age with moderately to severely (Crohn's Disease Activity Index 220-450) active Crohn's Disease with or without fistula formation
  • Participants who were able to provide authorization to use and disclose information related to the study
  • Proven diagnosis of Crohn's Disease in accordance with international diagnostic criteria such as European Crohn's and Colitis Organization (ECCO) guidelines
  • Participants for whom the physician had initiated anti-Tumor Necrosis Factor treatment in accordance with Turkish Ministry of Health regulations and reimbursements

Exclusion

  • Participants who had a history of any kind of biological therapy and/or anti-Tumor Necrosis Factor treatments for Crohn's Disease or other indications
  • Participants who had septic complications (active infection and/or active tuberculosis (TB), undrained abscess)
  • Participants who had bowel obstructions and fibrotic strictures
  • Participants who had received any investigational drug within 30 days prior to the Visit 1 at baseline
  • For any reason, participants who were considered by the investigator to be unsuitable

Key Trial Info

Start Date :

May 1 2013

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

February 1 2016

Estimated Enrollment :

106 Patients enrolled

Trial Details

Trial ID

NCT01860846

Start Date

May 1 2013

End Date

February 1 2016

Last Update

June 16 2017

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