Status:
COMPLETED
Pneumococcal Carriage in Patients With Lower Respiratory Tract Infection (LRTI)
Lead Sponsor:
Liverpool University Hospitals NHS Foundation Trust
Conditions:
Lower Respiratory Tract Infections
Eligibility:
All Genders
18+ years
Brief Summary
We are interested in developing new and better ways of diagnosing the cause of lower respiratory tract infections including pneumonia. Currently we find the causal bug (bacteria or virus) in less than...
Detailed Description
STUDY DESIGN OVERVIEW Overall research aim To analyse pneumococcal carriage rates in patients hospitalised with LRTI. Primary endpoint Rate of pneumococcal carriage in patients hospitalised with L...
Eligibility Criteria
Inclusion
- Inclusion criteria for LRTI patients:
- Non-pneumonic LRTI (no radiological consolidation but the presence of clinical signs) or community acquired pneumonia (radiological consolidation) Able to give fully informed consent (mental capacity assessed using trust guidelines) Age\>18yrs old Fluent English speaker
- Exclusion criteria for LRTI patients:
- Infective exacerbation of COPD or bronchiectasis without consolidation Oxygen saturations \<86% on air Tuberculosis suspected Neutropenia
- Inclusion criteria for controls:
- Able to give fully informed consent (mental capacity assessed using trust guidelines) Age\>18yrs old
- 10 years of recruited LRTI patient Fluent English speaker
- Exclusion criteria for controls:
- Signs/symptoms of respiratory infection Oxygen saturations \<86% on air Neutropenia
Exclusion
Key Trial Info
Start Date :
January 1 2013
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
November 1 2014
Estimated Enrollment :
38 Patients enrolled
Trial Details
Trial ID
NCT01861184
Start Date
January 1 2013
End Date
November 1 2014
Last Update
June 9 2022
Active Locations (1)
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1
Royal Liverpool University Hospital
Liverpool, United Kingdom, L7 8XP