Status:
COMPLETED
Prevalence of Hyperventilation Syndrome in Difficult Asthma
Lead Sponsor:
Assistance Publique - Hôpitaux de Paris
Conditions:
Difficult Asthma
Severe Persistent Asthma
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Most of asthmatics patients remain uncontrolled despite an inhaled steroids treatment. Chronic hyperventilation syndrome (also called Idiopathic Hyperventilation) occurs in 20 to 40% of asthmatic pati...
Detailed Description
There is only one visit. During this visit, each patient will complete self-questionnaires like Nijmegen, Hospital Anxiety and Depression Scale(HAD), Short-Form 36(SF36), and Asthma Quality of Life Qu...
Eligibility Criteria
Inclusion
- men and women,
- aged more than 18,
- non smokers for two years or longer, less than 10 pack/years smoking history,
- physician-diagnosed asthma,
- uncontrolled asthma with Asthma control test (ACT) \< 18,
- historical of FEV1 reversibility,
- daily inhaled steroids treatment by at least 2000microg eq beclomethasone,
- Forced expiratory volume in 1 second (FEV1) \> 50% predicted value
Exclusion
- other chronic pulmonary disease,
- vocal cord dysfunction,
- pregnancy,
- Participation in another interventional research trial,
- unable to provide consent,
- asthma exacerbation within the last 4 weeks
Key Trial Info
Start Date :
April 28 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 18 2016
Estimated Enrollment :
151 Patients enrolled
Trial Details
Trial ID
NCT01862289
Start Date
April 28 2013
End Date
October 18 2016
Last Update
May 1 2018
Active Locations (1)
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1
Assistance Publique - Hôpitaux de Paris, Bicêtre Hospital
Le Kremlin-Bicêtre, France, 94 275