Status:
UNKNOWN
Renal Resistive Index and Cardiac Output Changes During Resuscitation Predict the Occurrence of Acute Kidney Injury in Septic Shock Patients
Lead Sponsor:
Zhongda Hospital
Conditions:
Critically Ill
Acute Kidney Injury
Eligibility:
All Genders
18-90 years
Brief Summary
Record the renal resistive index and hemodynamic parameters ( record the cardiac output and stroke volume if the patient's next to kin agree to undertake a PiCCO monitoring ) before and after resuscit...
Detailed Description
* Purpose: To examine whether the resuscitation-induced changes of renal resistive index or hemodynamic parameters has the superiority as a valid tool to evaluate the renal perfusion improvement and w...
Eligibility Criteria
Inclusion
- ≥18 years, Sex unlimited
- Arriving ICU in 6 hours and diagnosed with severe sepsis or septic shock
- Physician in charge decide that an aggressive fluid resuscitation was in order
Exclusion
- Pregnancy, Age \<18 years
- Ongoing recovery from AKI
- Known end-stage renal disease or chronic kidney disease(glomerular filtration rate \<30mL/min/1.73m2)
- Known other causes of shock morbidly
- conditions known to modify RRI, such as renal-artery stenosis, intra-abdominal hypertension(\>35cmH2O)
Key Trial Info
Start Date :
January 1 2013
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
January 1 2014
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT01862588
Start Date
January 1 2013
End Date
January 1 2014
Last Update
January 15 2014
Active Locations (1)
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1
Affiliated Zhongda Hospital of Southeast University
Nanjing, Jiangsu, China, 210009