Status:
COMPLETED
Two Different Dosages of Nebulized Steroid Versus Parenteral Steroid in the Management of COPD Exacerbations
Lead Sponsor:
Ataturk University
Conditions:
Chronic Obstructive Pulmonary Disease
Eligibility:
All Genders
40-90 years
Phase:
PHASE4
Brief Summary
Chronic obstructive pulmonary disease (COPD) is a common disease that has a chronic and progressive course. Patients with COPD may have exacerbations one to four times in a year. Numbers of exacerbati...
Detailed Description
Study Population One hundred twenty patients with moderate or severe COPD exacerbation who are older than 40-years-old, had a smoking history of at least 10-pack-years and requiring hospitalization we...
Eligibility Criteria
Inclusion
- Patients with moderate or severe COPD exacerbation who are older than 40-years-old
- A smoking history of at least 10-pack-years
- Requiring hospitalization because of COPD exacerbation
Exclusion
- Presence of asthma, allergic rhinitis, atopy or any systemic disease (such as diabetes mellitus or hypertension)
- Exposed to systemic corticosteroids in the preceding month or used more than 1,500 microg/d of inhaled beclomethasone equivalent
- Admission to the intensive care unit (pH\<7.30 and/or PaCO2 \> 70 mm Hg, and/or PaO2 \< 50 mm Hg despite supplemental oxygen)
- If a specific cause for the exacerbation, such as pneumonia, pneumothorax, or heart failure, was diagnosed.
Key Trial Info
Start Date :
January 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2013
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT01865500
Start Date
January 1 2013
End Date
May 1 2013
Last Update
May 31 2013
Active Locations (1)
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1
Ataturk University Faculty of Medicine Pulmonary Disease Department
Erzurum, Turkey (Türkiye), 25240