Status:

COMPLETED

Pilot Study of the Safety of a Daily Ethanol Lock for Urinary Catheters in Critically Ill Children

Lead Sponsor:

Children's Healthcare of Atlanta

Conditions:

Complication of Urinary Catheter

Eligibility:

All Genders

6-17 years

Phase:

PHASE1

Brief Summary

Hypothesis 1: Blood alcohol concentration will be \<25 mg/100ml (equivalent to a blood alcohol concentration of \<0.025%) after a 1 hour urinary catheter ethanol lock. Hypothesis 2: Daily urinary cat...

Detailed Description

This study involves a confirmatory/refuting approach to the above stated hypothesis. The investigators will test this hypothesis by addressing the following aims/objectives: Specific Aim 1: Quantify...

Eligibility Criteria

Inclusion

  • Age: 6 months - 17 years
  • Urinary catheter placed at Children's Healthcare of Atlanta
  • Anticipated urinary catheter need for \> 48 hours
  • Parent or legal guardian (or patient when applicable) consent for enrollment.

Exclusion

  • 18 yo or older.
  • Urosepsis at time of study enrollment
  • Known bladder or genitourinary abnormalities
  • Chronic bladder drainage regimen
  • Urologic surgeries (as part of the current admission)
  • Medical urgency preventing timely administration of the consenting process, or any condition that, in the opinion of the attending physician, would place the patient at undue risk by participating.
  • Anuria or oliguria (\<0.5 cc/kg/hr averaged over the previous 12 hours)
  • Other technical considerations that would prevent the timely acquisition of sufficient samples such as (but not limited to) absence of a study team member.
  • Parent or legal guardian (or patient when applicable) refuses to sign informed consent.

Key Trial Info

Start Date :

July 1 2013

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 1 2015

Estimated Enrollment :

10 Patients enrolled

Trial Details

Trial ID

NCT01865708

Start Date

July 1 2013

End Date

June 1 2015

Last Update

June 28 2018

Active Locations (1)

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1

Children's Helathcare of Atlanta at Egleston

Atlanta, Georgia, United States, 30329