Status:

COMPLETED

A Retrospective, Observational Chart Review of Biologics in Monotherapy Versus the Combination Biologic Plus Methotrexate in Patients With Rheumatoid Arthritis

Lead Sponsor:

Hoffmann-La Roche

Conditions:

Rheumatoid Arthritis

Eligibility:

All Genders

18+ years

Brief Summary

This cross-sectional, non-interventional, retrospective chart review will compare the efficacy and safety of biologic monotherapy and biologic and methotrexate combination therapy in patients with rhe...

Eligibility Criteria

Inclusion

  • Adult patients, \>/= 18 years of age
  • Diagnosis of rheumatoid arthritis by a rheumatologist
  • Patients who have responded inadequately to methotrexate or disease-modifying anti-rheumatic drugs (DMARDs) and are being prescribed a biologic in monotherapy or in combination with methotrexate and other classical DMARDs as per NICE guidelines

Exclusion

  • Primary diagnosis of a condition other than rheumatoid arthritis
  • Current treatment with a biologic in combination without methotrexate
  • Prior treatment with an experimental agent for rheumatoid arthritis

Key Trial Info

Start Date :

April 1 2013

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

March 1 2014

Estimated Enrollment :

476 Patients enrolled

Trial Details

Trial ID

NCT01866150

Start Date

April 1 2013

End Date

March 1 2014

Last Update

October 5 2015

Active Locations (15)

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Page 1 of 4 (15 locations)

1

Cambridge, United Kingdom, CB2 0QQ

2

Chelmsford, United Kingdom, CM1 7ET

3

Cosham, United Kingdom, PO6 3LY

4

Derby, United Kingdom, DE22 3NE

A Retrospective, Observational Chart Review of Biologics in Monotherapy Versus the Combination Biologic Plus Methotrexate in Patients With Rheumatoid Arthritis | DecenTrialz