Status:

COMPLETED

A Study to Compare Efficacy and Safety of an Ovule Containing Terconazole, Clindamycin and Fluocinolone Versus an Ovule Containing Metronidazole, Nystatin and Fluocinolone in the Treatment of Secondary Vulvar/ or Vaginal Symptoms of Infectious Vaginitis/ and Infectious Vaginosis

Lead Sponsor:

Janssen-Cilag, S.A.

Conditions:

Vaginitis

Infectious Vaginosis

Eligibility:

FEMALE

18-75 years

Phase:

PHASE3

Brief Summary

The purpose of this comparative study is to evaluate the efficacy of an ovule with triple active agents (terconazole, clindamycin and fluocinolone) versus another ovule with triple active agents (nyst...

Detailed Description

This is a prospective (study following participants forward in time), open-label (all people know the identity of the intervention), randomized (the study drug is assigned by chance), comparative, par...

Eligibility Criteria

Inclusion

  • Participants presenting clinical symptoms compatible with vaginitis/bacterial vaginosis, with any of the following symptoms being the reason for the consultation: pruritus (itchiness), vulvar burning, as well as presenting leukorrhea (a clear or white discharge from the vagina, consisting mainly of mucus) as an accompanying symptom
  • Participant who agrees to return at the 7th and 13th day after starting the treatment
  • Participant who agrees to abstain from sexual relations for the 13 days of the study
  • Participant who have signed informed consent to participate in the study

Exclusion

  • Participant with a known allergy to vaginal treatments
  • Participants who have received treatment for the current condition in the 10 days before the date of inclusion, or is currently receiving antibiotics (drug used to stop or slow down the growth of germs), antifungals, anti-parasitics or systemic steroids
  • Participant with suspected pregnancy or currently breastfeeding
  • Participant who has received unknown drugs or experimental drugs within the 3 months before inclusion
  • Participant known to be a carrier of a severe (very serious, life threatening) disease that alters the metabolism or excretion of the drugs used (liver or kidney disease)

Key Trial Info

Start Date :

December 1 2007

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 1 2008

Estimated Enrollment :

160 Patients enrolled

Trial Details

Trial ID

NCT01867164

Start Date

December 1 2007

End Date

December 1 2008

Last Update

December 24 2013

Active Locations (2)

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Page 1 of 1 (2 locations)

1

DF, Mexico City, Mexico

2

Mexico City, Mexico