Status:
COMPLETED
Assessing the Impact of Calcium Channel Blockers on COGnitive Function in the Very Elderly (AI-COG)
Lead Sponsor:
Imperial College London
Conditions:
Cognitive Ability, General
High Blood Pressure
Eligibility:
All Genders
80+ years
Brief Summary
Older adults are at increased risk of high blood pressure and cognitive decline. High blood pressure itself also increases risk of cognitive decline. A particular type of blood pressure lowering drug ...
Detailed Description
This study is an observational cohort study examining cognitive change in those participants taking antihypertensives and aged 80 and over and examining cognitive change in participants taking differe...
Eligibility Criteria
Inclusion
- Aged 80 and over Receiving pharmacological treatment for hypertension Mini Mental State Exam score \>24 No other condition likely to limit life to less than one year or to prevent the taking of informed consent.
Exclusion
- Aged under 80 years Not receiving pharmacological treatment for hypertension Mini Mental State Exam score \<25 Diagnosed with a condition likely to limit life to less than one year or to prevent the taking of informed consent.
- Presence of a sensory impairment or an existing neuropsychological deficit of sufficient severity to prevent cognitive testing.
- Presence of a condition that will prevent cognitive testing, registered blind, profoundly deaf, suffering from an aphasia.
Key Trial Info
Start Date :
June 1 2013
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
February 1 2016
Estimated Enrollment :
337 Patients enrolled
Trial Details
Trial ID
NCT01868165
Start Date
June 1 2013
End Date
February 1 2016
Last Update
September 23 2019
Active Locations (7)
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1
The Kiltearn Medical Centre
Nantwich, Cheshire, United Kingdom, CW5 5NX
2
Ashfields Primary Care Centre
Sandbach, Cheshire, United Kingdom, CW11 BEQ
3
Whitby Group Practice
Whitby, North Yorkshire, United Kingdom, YO21 1SD
4
South Axholme Practice
Epworth, Yorkshire, United Kingdom, DN9 1EP