Status:

COMPLETED

DTI of the Brain and Cervical Spine: Evaluation in Normal Subjects and Patients With Cervical Spondylotic Myelopathy

Lead Sponsor:

Emory University

Collaborating Sponsors:

Siemens Medical Solutions

Conditions:

Cervical Spondylosis With Myelopathy

Eligibility:

All Genders

30-70 years

Brief Summary

More than half of the middle-aged population has radiologic evidence of cervical spondylosis (Irvine 1965) and a subset of this population develops cervical spondylotic myelopathy (CSM), a condition i...

Detailed Description

More than half of the middle-aged population has radiologic evidence of cervical spondylosis and a subset of this population develops cervical spondylotic myelopathy (CSM), a condition in which the sp...

Eligibility Criteria

Inclusion

  • 20 patients will be selected by an experienced team of orthopedic specialist from the Emory Orthopaedics \& Spine Center and will include patients suffering signs and symptoms of cervical myelopathy and with evidence of radiographic cervical cord compression with or without abnormal spinal cord signal intensity secondary to spondylosis.
  • 20 controls : Aged matched to the patient group. No history of CSM.

Exclusion

  • Any history of significant trauma implicating the brain or cervical spine, including prior motor vehicle collision and history of prior brain, neck or cervical spine surgery.
  • Any history of neurological disease
  • Dental braces or similar orthodontic devices.
  • Claustrophobia

Key Trial Info

Start Date :

January 1 2013

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

June 1 2015

Estimated Enrollment :

26 Patients enrolled

Trial Details

Trial ID

NCT01868958

Start Date

January 1 2013

End Date

June 1 2015

Last Update

July 15 2015

Active Locations (1)

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1

Center for Systems Imaging (CSI), Emory University

Atlanta, Georgia, United States, 30329