Status:
COMPLETED
Comparison of IV Ergonovine With IM Carboprost, With Oxytocin IV, During Cesarean Section for Failure to Progress
Lead Sponsor:
Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Conditions:
Postpartum Hemorrhage
Eligibility:
FEMALE
14-55 years
Phase:
NA
Brief Summary
Patients having Cesarean section after they have been in labor for many hours bleed much more, in average twice as much, as compared with patients having an elective Cesarean section. The investigator...
Detailed Description
The objective of the investigators study is to compare the efficacy of intravenous ergonovine and intramuscular carboprost, when administered with oxytocin infusion, prophylactically to decrease blood...
Eligibility Criteria
Inclusion
- patients who give written informed consent
- patients undergoing Cesarean section for failure to progress in labour, under regional anesthesia
- patients should be in the first stage of labour and have received oxytocin for at least 4 hours
Exclusion
- patients who refuse to give written informed consent
- patients who require general anesthesia
- patients who claim allergy or hypersensitivity to oxytocin, ergot derivatives or prostaglandins
- patients with cardiac diseases and hypertension or preeclampsia ( diastolic blood pressure \> 90 mmHg, systolic blood pressure \> 140 mmHg )
- patients with asthma or any other respiratory disease
- patients with conditions at risk of PPH such as placenta previa, multiple gestation, preeclampsia, macrosomia, polyhydramnios, uterine fibroids, previous history of uterine atony and postpartum bleeding, bleeding diathesis and known infection.
Key Trial Info
Start Date :
June 4 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 30 2019
Estimated Enrollment :
105 Patients enrolled
Trial Details
Trial ID
NCT01869556
Start Date
June 4 2013
End Date
September 30 2019
Last Update
September 24 2020
Active Locations (1)
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1
Mount Sinai Hospital
Toronto, Ontario, Canada, M5G1X5