Status:

COMPLETED

Evaluation of Fats on Postprandial Glucose Control

Lead Sponsor:

Joslin Diabetes Center

Collaborating Sponsors:

Boston Children's Hospital

Conditions:

Type 1 Diabetes

Eligibility:

All Genders

18-75 years

Phase:

NA

Brief Summary

The purpose of this study is examine the effect of different fat types on postprandial glucose control in patients with type 1 diabetes. Subjects will have several admissions and, in random order, wi...

Detailed Description

Subjects for this study will be adults with type 1 diabetes who use insulin pump in their diabetes self-management. Prior to admission the the clinical research center the basal rates and insulin-to-c...

Eligibility Criteria

Inclusion

  • Adult patients (aged 18-75 years) with type 1 diabetes \> 3 years.
  • On insulin pump therapy.
  • A1c \< 8.5%.

Exclusion

  • History or symptoms suggestive of gastric dysmotility, celiac disease, pancreatic exocrine dysfunction or other conditions that cause malabsorption or maldigestion.
  • Eating disorder.
  • Diet allergies.
  • Special diet restrictions, such as vegan or any nut allergy.
  • Medications know to affect insulin sensitivity (such as glucocorticoids) or affect gastrointestinal motility (such as reglan).
  • High-titre insulin autoantibodies with delayed insulin kinetics.
  • Women who are breast feeding, pregnant, or wanting to become pregnant.

Key Trial Info

Start Date :

June 1 2013

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

April 1 2015

Estimated Enrollment :

10 Patients enrolled

Trial Details

Trial ID

NCT01869790

Start Date

June 1 2013

End Date

April 1 2015

Last Update

April 26 2017

Active Locations (1)

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Joslin Diabetes Center

Boston, Massachusetts, United States, 02215