Status:
COMPLETED
Effect of 10-day Overnight Hypoxia Treatment on Whole Body Insulin Sensitivity (SLEEP HIGH Study)
Lead Sponsor:
Pennington Biomedical Research Center
Conditions:
Insulin Resistance
Eligibility:
MALE
20-45 years
Phase:
EARLY_PHASE1
Brief Summary
The purpose of this study is to look at how a reduction in oxygen levels (hypoxia) influences insulin sensitivity and carbohydrate metabolism. It is expected that 10 nights of exposure to moderate hyp...
Eligibility Criteria
Inclusion
- Aged 20-45 years
- Male
- Obese category (BMI \> 30 kg/m2)
- Healthy as assessed by a self-reported health questionnaire
- Non-smokers
- Weight stable over the past 3 months (\<2kg fluctuation)
Exclusion
- Female
- Diabetes
- Sleep apnea
- Hypertension
- History of altitude sickness
- Individuals taking any chronic medications
- Individuals taking any stimulants
- Individuals taking beta-blockers
- Individuals with chronic alcohol consumption (\>3 drinks per day) or drug abuse.
- Individuals unable to abstain from caffeinated beverage or alcohol the days of study testing
- Individuals with history disease or history of stroke
Key Trial Info
Start Date :
July 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2013
Estimated Enrollment :
9 Patients enrolled
Trial Details
Trial ID
NCT01872533
Start Date
July 1 2011
End Date
May 1 2013
Last Update
December 2 2015
Active Locations (1)
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1
Pennington Biomedical Research Center
Baton Rouge, Louisiana, United States, 70808