Status:
COMPLETED
Comparative Study Menaquinone-7
Lead Sponsor:
Maastricht University Medical Center
Conditions:
Bioavailability
Eligibility:
All Genders
45-65 years
Phase:
NA
Brief Summary
The objective of this study is to investigate the absorption of menaquinone-7 from a nutrient-enriched dairy product compared to a general dairy product enriched with menaquinone-7 and a menaquinone-7...
Detailed Description
In an earlier study, beneficial effects of a nutrient-enriched dairy product on vitamin K-status were observed. The study product contained menaquinone-7 (MK-7) and omega-3 fatty acids for vascular he...
Eligibility Criteria
Inclusion
- Apparently healthy men and postmenopausal women between 45 and 65 years old
- Subjects with body weight and height according to BMI between 20 and 30 kg/m2
- Subjects of Caucasian race
- Subject has given written consent to take part in the study
Exclusion
- Subjects with hypertension
- Subjects with hypercholesterolemia
- Subjects with (a history of) metabolic or gastrointestinal disease
- Subjects presenting chronic degenerative and/or inflammatory disease
- Subjects with (a history) of diabetes mellitus
- Abuse of drugs and/or alcohol
- Subjects receiving corticosteroid treatment
- Subjects using oral anticoagulants and subjects with clotting disorders
- Subjects using blood pressure-lowering medication
- Subjects using cholesterol-lowering medication
- Subjects using multivitamins or vitamin K supplements
- Subjects consuming high amounts of vitamin K-containing food products
- Subjects with cow's milk allergy and lactose intolerance
Key Trial Info
Start Date :
April 1 2012
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2013
Estimated Enrollment :
107 Patients enrolled
Trial Details
Trial ID
NCT01873274
Start Date
April 1 2012
End Date
May 1 2013
Last Update
June 13 2013
Active Locations (1)
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1
VitaK BV / Maastricht University Medical Center
Maastricht, Netherlands, 6229 EV