Status:
UNKNOWN
Verify the Effectiveness rTMS Using MEG
Lead Sponsor:
Seoul National University Hospital
Conditions:
Tinnitus
Eligibility:
All Genders
18-70 years
Phase:
NA
Brief Summary
The purpose of this study is to determine whether rTMS are effective in the treatment of tinnitus
Detailed Description
Repetitive transcranial magnetic stimulation (rTMS) of the dorsolateral prefrontal cortex (DLPFC) has an add-on effect for primary auditory cortex rTMS in improving tinnitus-related distress. We aimed...
Eligibility Criteria
Inclusion
- Diagnosis of chronic tinnitus
- Chronic subjective tinnitus for more than 6 months
- Pure tone average \<50 dB HL in the ear where tinnitus is perceived
- Dominant tinnitus frequency measured between 4 and 8 kHz
- Subject is naive regarding rTMS
- Other concurrent treatments: A four-week washout from any other tinnitus
- treatment or management program is required prior to entering this study
- Stable enough to complete this study per the opinion of the Study Physician
- No restrictions, provided the dosages have been in place for at least 3 months
- A three month washout from any other tinnitus treatment or management program is required prior to entering this study.
Exclusion
- Objective tinnitus or tinnitus with treatable cause
- Absolute thresholds \> 60 dB on individual frequencies up to 8 kHz
- Presence of intracranial or intraocular ferromagnetic materiel or particles Cardiac pacemaker or other electronic implants (including cochlear implant)
- Serious heart disease or other unstable major medical condition
- Personal history of central nervous system disorder, head injury, stroke or seizures
- Familial history of epilepsy;
- Concomitant medication with antidepressants and antipsychotics
- Pregnant women
- Severe depression
- Severe anxiety
- Others known contraindications to rTMS or brain MRI
Key Trial Info
Start Date :
May 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2015
Estimated Enrollment :
28 Patients enrolled
Trial Details
Trial ID
NCT01874444
Start Date
May 1 2013
End Date
December 1 2015
Last Update
November 19 2014
Active Locations (1)
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1
Seoul National University Hospital
Seoul, South Korea