Status:
COMPLETED
Patients With Chronic Obstructive Pulmonary Disease At Altitude
Lead Sponsor:
University of Zurich
Conditions:
Chronic Obstructive Pulmonary Disease (COPD)
Eligibility:
All Genders
18-75 years
Phase:
NA
Brief Summary
The purpose of this study is to investigate the effect of a stay at moderate altitude on exercise performance of patients with chronic obstructive lung disease.
Detailed Description
Patients with moderate to severe COPD living below 800 m, will be recruited to participate in a randomized cross-over field trial evaluating the hypothesis that exercise capacity during a 4 day sojour...
Eligibility Criteria
Inclusion
- chronic obstructive pulmonary disease (COPD), GOLD grade 2-3
- residents at low altitude (\<800 m)
Exclusion
- Unstable condition, COPD exacerbation
- Mild (GOLD 1) or very severe COPD (GOLD 4)
- requirement for oxygen therapy at low altitude residence
- hypoventilation
- pulmonary hypertension
- more than mild or unstable cardiovascular disease
- use of drugs that affect respiratory center drive
- internal, neurologic or psychiatric disease that interfere with protocol compliance including current heavy smoking (\>20 cigarettes per day), inability to perform 6 min walk test.
- previous intolerance to moderate altitude (\<2600m).
- Exposure to altitudes \>1500m for \>2 days within the last 4 weeks before the study.
- Pregnant or nursing patients
Key Trial Info
Start Date :
May 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2013
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT01875133
Start Date
May 1 2013
End Date
December 1 2013
Last Update
May 19 2015
Active Locations (1)
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1
University Hospital Zurich, Pulmonary Division
Zurich, Switzerland, CH-8091