Status:

UNKNOWN

Effectiveness of Low Energy Laser Treatment in Oral Mucositis Induced by Chemotherapy and Radiotherapy in Head and Neck Cancer

Lead Sponsor:

Fundación Pública Andaluza Progreso y Salud

Conditions:

Oral Mucositis

Eligibility:

All Genders

18-80 years

Phase:

PHASE4

Brief Summary

The purpose of this study is to evaluate the effectiveness of using to low intensity laser as an intervention against preventive and therapeutic oral mucositis induced by radiotherapy and chemotherapy...

Eligibility Criteria

Inclusion

  • Patients diagnosed with squamous cell carcinoma of the oral cavity.
  • Patients aged between 18 and 80 years.
  • Patients who are to receive one of the following treatment
  • Combined radiotherapy (conventional fractionation 70 Gy reaching the tumor and affected lymph nodes, and 50 Gy in the areas ganglion drainage) and chemotherapy (cisplatin 100 mg/m2 IV on days 1, 22 and 43 irradiation or cetuximab 400mg/m2 as a single dose pre-load radiotherapy and 250mg/m2 weekly for the same. Regardless of whether they have received previous surgical treatment.
  • Treatment with radiotherapy of 70 Gy in 35 daily sessions 2Gy/día consecutive.
  • Patients who voluntarily express their intention to participate by informed consent.

Exclusion

  • Patients who denied informed consent.
  • Patients who have hypersensitivity or allergy to any of the components included in the study.
  • Patients diagnosed with HIV, and autoimmune diseases.

Key Trial Info

Start Date :

January 1 2013

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

July 1 2016

Estimated Enrollment :

126 Patients enrolled

Trial Details

Trial ID

NCT01876407

Start Date

January 1 2013

End Date

July 1 2016

Last Update

February 5 2016

Active Locations (1)

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1

Hospital Universitario Virgen del Rocío

Seville, Spain, 41013