Status:
COMPLETED
Impact of Vitamin B12 Replacement on Epogen Dosing and Improvement of Quality of Life in Hemodialysis Patients
Lead Sponsor:
Northwell Health
Collaborating Sponsors:
Staten Island University Hospital
Conditions:
Vitamin B12 Deficiency
Eligibility:
All Genders
18-90 years
Phase:
NA
Brief Summary
Vitamin B12 has several important functions in the body, two of which are production of red blood cells and the maintenance of a healthy nervous system. When vitamin B12 is deficient, abnormal red blo...
Detailed Description
BACKGROUND: Vitamin B12 deficiency may have deleterious effects on end stage renal disease (ESRD) patients on maintenance hemodialysis, and may increase erythropoietin stimulating agent (ESA) resistan...
Eligibility Criteria
Inclusion
- · Patients on Hemodialysis for at least 6 months
- Patients on stable dose of epogen and iron supplementation for at least 1 month prior to B12 and MMA assay.
Exclusion
- · On B12 treatment
- Hematological Cancer
- Methotrexate use
- Alcohol use greater then 2 drinks per day
- Vegetarian Diet
- Gastric Surgery
- Inflammatory Bowel Disease
- Pernicious Anemia
- Recent transfusion
Key Trial Info
Start Date :
June 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 1 2011
Estimated Enrollment :
132 Patients enrolled
Trial Details
Trial ID
NCT01876732
Start Date
June 1 2009
End Date
April 1 2011
Last Update
September 8 2014
Active Locations (1)
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1
Island Rehab
Staten Island, New York, United States, 10305