Status:
WITHDRAWN
Comparison of Reverse Remodeling and PVI Versus CFAE and/or Linear Lesions and PVI for Persistent AF
Lead Sponsor:
Valley Health System
Conditions:
Persistent Atrial Fibrillation
Eligibility:
All Genders
18-85 years
Phase:
PHASE4
Brief Summary
The hypothesis of this study is that by facilitating reverse atrial remodeling with maintenance of sinus rhythm in the weeks preceding ablation makes it feasible to perform a simple pulmonary vein iso...
Detailed Description
Atrial fibrillation (AF) is the most common cardiac disorder currently affecting 2.3 million U.S. adults with an expected increase in incidence to 5.6 million by the year 2050. Randomized clinical tri...
Eligibility Criteria
Inclusion
- Symptomatic persistent AF
- Failure of class I antiarrhythmic drug or amiodarone to control AF
Exclusion
- Previous proarrhythmia to class III AAD including excessive QT prolongation or torsade-de-pointes
- Previous AF ablation procedure
- Congestive heart failure (NYHA III-IV functional class)
- Left ventricle ejection fraction less than 35%
- Left atrial diameter \>55 mm
- Unwillingness to participate
Key Trial Info
Start Date :
May 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 1 2013
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT01877473
Start Date
May 1 2013
End Date
September 1 2013
Last Update
June 17 2014
Active Locations (1)
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1
Valley Hospital
Ridgewood, New Jersey, United States, 07450