Status:

COMPLETED

Utility of a Weaning Protocol in ICU

Lead Sponsor:

ELENA PELI,MD

Conditions:

Weaning Failure

Eligibility:

All Genders

Brief Summary

The purpose of this study is to evaluate the difference of the duration of weaning process from the ventilator between protocol-driven weaned patients and clinical judgment driven weaned patients.

Detailed Description

All patients with prolonged weaning and who required tracheostomy are enrolled in the study. These patients are randomized as "Case or Control" by a computer program. Patients can start the weaning p...

Eligibility Criteria

Inclusion

  • all patients that are clinically identified as prolonged to wean (failed 3 spontaneous breathing trials or 7 days or more of mechanical ventilation after the initial unsuccessful trial) and tracheostomized in ICU
  • improvement or resolution of the underlying causes of acute respiratory failure ratio between pressure partial artery of oxygen and fraction inspired oxygen (PaO2/FiO2) \>200 with fraction inspired oxygen (FiO2)\< 0,45.
  • pressure supported ventilation at the time of enrollment.

Exclusion

  • patients assessed as easy weaning and not tracheostomized;
  • patients already tracheostomized on admission to ICU.

Key Trial Info

Start Date :

May 1 2013

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

May 1 2014

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT01877850

Start Date

May 1 2013

End Date

May 1 2014

Last Update

April 23 2015

Active Locations (1)

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1

Institute of Anesthesiology and Intensive Care of the University of Brescia, Spedali Civili, Italy,

Brescia, Brescia, Italy, 25128