Status:
COMPLETED
Assessment of Lumen Expansion After Thrombus Extraction in Primary Percutaneous Coronary Intervention
Lead Sponsor:
Newcastle-upon-Tyne Hospitals NHS Trust
Conditions:
Acute ST Elevation Myocardial Infarction
Eligibility:
All Genders
18-75 years
Phase:
NA
Brief Summary
To use IVUS to assess (1) culprit plaque morphology and thrombus burden in patients with ST-elevation myocardial infarction; (2) the efficacy of thrombus removal with an aspiration catheter in 40 pati...
Detailed Description
Primary PCI has become the preferred therapy for ST-elevation acute myocardial infarction. The TAPAS trial data suggests that widespread adoption of manual thrombus aspiration may improve clinical out...
Eligibility Criteria
Inclusion
- patients 18-75 years old with myocardial infarction with ST-segment elevation
- symptoms of myocardial ischemia lasting more than 30 minutes
- onset of symptoms within 12 hours of hospital presentation
- ST-segment elevation of more than 0.1 mV in two or more leads on the ECG
Exclusion
- inability to obtain informed consent
- use of fibrinolytic drug within 12 hours of presentation
- comorbidity with anticipated life expectancy of \< 6 months
- cardiogenic shock on presentation
- major bleeding diathesis
- history of aspirin and clopidogrel intolerance
- critical left main stem lesions
- severe calcfic disease precluding safe passage of the imaging catheter
- culprit lesion within saphenous vein grafts
- \-
Key Trial Info
Start Date :
January 1 2012
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2013
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT01878487
Start Date
January 1 2012
End Date
May 1 2013
Last Update
October 12 2015
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Department of Cardiology, Freeman Hospital
Newcastle, United Kingdom