Status:
COMPLETED
Endothelial Function in Obese Adolescents
Lead Sponsor:
Montefiore Medical Center
Conditions:
Insulin Resistance
Glucose Intolerance
Eligibility:
All Genders
12-18 years
Phase:
NA
Brief Summary
Childhood obesity is perhaps the most significant public health problem in the most developed countries and is rapidly becoming so in developing countries. National Health and Nutrition Examination Su...
Detailed Description
Following informed consent, a detailed history and physical examination will be performed including supine blood pressure taken twice after a 20 minute period of rest, height (using Harpenden stadiome...
Eligibility Criteria
Inclusion
- Children in the age range of 12-18 years
- For the lean group, age and sex matched subjects with BMI between 5th-85th percentiles
- Obese group defined as BMI ≥95th percentile. These will further be subgrouped into those with normal and those with abnormal glucose tolerance normal glucose tolerance (NGT) defined as fasting glucose level\<100mg/dl and a 2 hour postprandial glucose level\<140mg/d and abnormal OGTT defined as fasting level ≥100mg/dl and/or 2hr ≥140 using a glucose load of 1.75 g/kg body weight (max 75 g).Hence, we will
Exclusion
- \-
Key Trial Info
Start Date :
March 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 1 2014
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT01879033
Start Date
March 1 2011
End Date
January 1 2014
Last Update
January 22 2019
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Albert Einstein College of Medicine West Campus Clinical Research Center
The Bronx, New York, United States, 10467