Status:
UNKNOWN
Study of Standardized Treatment of Integrative Medicine With the Severe IgA Nephropath
Lead Sponsor:
Shanghai University of Traditional Chinese Medicine
Collaborating Sponsors:
Shanghai 6th People's Hospital
RenJi Hospital
Conditions:
IgA Nephropathy
Eligibility:
All Genders
18-60 years
Phase:
NA
Brief Summary
IgA nephropathy(IgAN) is the highest incidence of kidney pathology in the primary nephropathy. In terms of differences in prognosis, severe IgA nephropathy,one of the most main primary renal disease,c...
Eligibility Criteria
Inclusion
- Confirmed by renal biopsy and clinical examination as primary IgA nephropathy.
- Pathology:upon Lee's grade Ⅲ
- Age :18-60 years old.
- Gender and nationality are not limited
- Chronic Kidney Disease(CKD) Stage 3:（59 ml/min\>GFR\>30ml/min/1.73m2）
- 24-hour urine protein:≥1.0g.Informed consent
Exclusion
- Patients within the past 3 months had received immunosuppressive agents or cytotoxic therapy is greater than 4 weeks
- Patients within the past 3 months who have received corticosteroids (prednisone or prednisolone) dose of more than 20mg / d up to 4 weeks
- Patients suffering from acute or rapidly progressive glomerulonephritis
- Patients continue with active hepatitis B and abnormal liver function tests transaminase
- Patients with a history of malignant tumor or malignancy, HIV infection, history of mental illness, acute central nervous system disorders, severe gastrointestinal disease, prohibiting the use of immunosuppressive agents
- Abnormal glucose metabolism, fasting blood glucose more than 6.2mmol/L
- Pregnancy or breast-feeding women
- Receiving other clinical trials
- Associated with other serious diseases and organ dysfunction
- Combined life-threatening complications such as severe infection
Key Trial Info
Start Date :
January 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT01879514
Start Date
January 1 2010
Last Update
June 17 2013
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Department of Nephrology,Longhua Hospital
Shanghai, China, 200032