Status:
TERMINATED
Chronic Bladder Pain Syndrome in Women: Can Doxycycline Help? A Prospective Study
Lead Sponsor:
Insel Gruppe AG, University Hospital Bern
Conditions:
Chronic Pelvic Pain Syndrome
Bladder Pain Syndrome
Eligibility:
FEMALE
18+ years
Phase:
PHASE4
Brief Summary
Chronic bladder pain syndrome is a chronic disabling disorder characterized by chronic pelvic pain, pressure or discomfort perceived to be related to the urinary bladder accompanied by at least one ot...
Detailed Description
Background Doxycycline is used to treat bacterial infections. Doxycycline is in a class of medications called tetracycline antibiotics. In addition to the general indications for all members of the t...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- Bladder pain / suprapubic pressure or discomfort for \>6months
- Urgency/urgency incontinence and/or frequency for \>6months
- Written informed consent (including confirmation that the partner will also be treated and that during the treatment period sexual intercourse is only allowed using condoms)
- Exclusion Criteria
- age \< 18 years
- Tetracycline allergy
- Intake of a tetracycline in the last 3 months
- pregnancy
- breast feeding
- bacterial cystitis in the last 4 weeks
- urethral/vaginal/cervical/uterine and/or rectal cancer
- chemical cystitis
- tuberculous cystitis
- benign or malignant bladder tumors
- Lack of radiologic exclusion of pelvic pathology
Exclusion
Key Trial Info
Start Date :
November 1 2012
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2015
Estimated Enrollment :
5 Patients enrolled
Trial Details
Trial ID
NCT01879930
Start Date
November 1 2012
End Date
March 1 2015
Last Update
March 5 2015
Active Locations (1)
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1
Dep. of Urology, Bern University Hospital
Bern, Canton of Bern, Switzerland, 3010