Status:

COMPLETED

rTMS for Working Memory Deficits in Schizophrenia

Lead Sponsor:

Centre for Addiction and Mental Health

Collaborating Sponsors:

Canadian Institutes of Health Research (CIHR)

Conditions:

Schizophrenia

Schizoaffective Disorder

Eligibility:

All Genders

18-59 years

Phase:

NA

Brief Summary

In this study, the investigators will be examining the effects of repetitive transcranial magnetic stimulation (rTMS) on memory deficits in individuals with schizophrenia and schizoaffective disorder....

Detailed Description

This study is a randomized, double blind, sham controlled study to evaluate the efficacy of repetitive transcranial magnetic stimulation as a treatment for working memory deficits in individuals with ...

Eligibility Criteria

Inclusion

  • Between 18 and 59 years of age
  • Current diagnosis of Schizophrenia or Schizoaffective Disorder
  • Able to provide written informed consent
  • Fluency in the English Language

Exclusion

  • Have a history of substance abuse or dependence in the last 6 months
  • Have a concomitant major and unstable medical or neurologic illness
  • Have a history of seizures or have a first degree relative with a history of a seizure disorder
  • Current pregnancy or a plan to become pregnant during the duration of the study
  • Clinical instability: determined by treating physician
  • Have received electroconvulsive therapy (ECT) within the last year
  • Have a history of repetitive transcranial magnetic stimulation (rTMS)
  • Are taking a benzodiazepine at a dose greater than Lorazepam 2mg or equivalent
  • Are taking any non-benzodiazepine anticonvulsant
  • Have a cardiac pacemaker, cochlear implant, implanted electronic device or non-electric metallic implant

Key Trial Info

Start Date :

June 1 2013

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 7 2019

Estimated Enrollment :

81 Patients enrolled

Trial Details

Trial ID

NCT01880255

Start Date

June 1 2013

End Date

January 7 2019

Last Update

July 11 2019

Active Locations (1)

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1

Centre for Addiction and Mental Health

Toronto, Ontario, Canada