Status:

COMPLETED

Effects of Resveratrol on Endothelial Function in Type 2 Diabetes Mellitus

Lead Sponsor:

Boston University

Collaborating Sponsors:

National Heart, Lung, and Blood Institute (NHLBI)

Conditions:

Diabetes Mellitus

Eligibility:

All Genders

21-75 years

Phase:

NA

Brief Summary

The present study is designed to test the hypothesis that resveratrol supplementation will improve the function of the endothelium in patients with type 2 diabetes mellitus. The function of the endot...

Eligibility Criteria

Inclusion

  • Male and female subjects
  • Age over 21 years old
  • Body mass index less than 38 kg/m2
  • Clinical stable type 2 diabetes mellitus

Exclusion

  • Women who are lactating or pregnant
  • Treatment with an investigations product within 30 days of screening
  • Clinically evident major illness of other organ systems, including cancer, renal failure, or other conditions in the opinion of the investigators that would make clinical study inappropriate
  • Liver transaminase levels greater than 3 times the upper limit of normal
  • History of psychological illness or condition that would interfere with the subject's ability to understand the requirements of the study
  • Vitamin supplements exceeding two times the recommended daily allowance
  • Resveratrol or other dietary supplements except for a daily multivitamin

Key Trial Info

Start Date :

January 1 2013

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 1 2016

Estimated Enrollment :

54 Patients enrolled

Trial Details

Trial ID

NCT01881347

Start Date

January 1 2013

End Date

July 1 2016

Last Update

March 1 2018

Active Locations (1)

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1

Boston University Medical Center

Boston, Massachusetts, United States, 02118