Status:

UNKNOWN

Anti TNF α Improves Endothelial Dysfunction in IBD Patients

Lead Sponsor:

Carmel Medical Center

Conditions:

Crohn's Disease

Eligibility:

All Genders

18-40 years

Brief Summary

Study hypothesis - this study will assess the presence of endothelial dysfunction in patients with Crohn's disease before and after 12 weeks treatment of anti TNF α.

Detailed Description

Crohn's Disease (CD) is a life long disease that mainly affects young adults. There is evidence That gut tissue injury is the result of an abnormal immune response that involved multiple non immune ce...

Eligibility Criteria

Inclusion

  • Non smoker
  • No history of IHD or other known risk factors for IHD

Exclusion

  • Patients who had been treated with anti TNF α 4 weeks before the study
  • As well as those who received corticosteroids within 1 week before the study.
  • DM, IHD, CRF, SMOKER

Key Trial Info

Start Date :

May 1 2014

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

June 1 2018

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT01881464

Start Date

May 1 2014

End Date

June 1 2018

Last Update

May 16 2014

Active Locations (1)

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Carmel Medical Center

Haifa, Israel