Status:

COMPLETED

The Prevalence of Coronary Spasm in Hypertensive Patients Treated With Antihypertensive Medication

Lead Sponsor:

Korea University

Collaborating Sponsors:

Korea Institute of Science and Technology

Conditions:

Coronary Artery Spasm

Hypertension

Eligibility:

All Genders

Brief Summary

Autonomic nerve function is involved in both blood pressure (BP) regulation and the pathogenesis of coronary artery spasm(CAS), but few studies have been published about the relationship between CAS a...

Detailed Description

A total of consecutive patients in the CAS registry of the Cardiovascular Center at Korea University Guro Hospital and who had resting chest pain without significant coronary lesions (luminal narrowin...

Eligibility Criteria

Inclusion

  • Hypertensive patients who are treated with antihypertensive drugs have resting chest pain without significant coronary lesions(luminal narrowing \<50%) underwent a provocation test with Ach infusion during coronary angiography.

Exclusion

  • Patients with documented cardiovascular disease and/or any other serious medical condition, such as an increased serum creatinine level(\>2mg/dl), patients with incomplete data, or patients who were not treated with antihypertensive agents

Key Trial Info

Start Date :

May 1 2013

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

August 1 2013

Estimated Enrollment :

1933 Patients enrolled

Trial Details

Trial ID

NCT01882790

Start Date

May 1 2013

End Date

August 1 2013

Last Update

August 27 2013

Active Locations (3)

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Page 1 of 1 (3 locations)

1

Department of Internal Medicine, Division of Cardiology, Sanbon Hospital, Wonkwang University College of Medicine

Gunpo, Gyeonggi-do, South Korea

2

Cardiovascular Center, Korea University Guro Hospital

Seoul, South Korea, 152-703

3

Korea Institute of Science and Technology

Seoul, South Korea