Status:
UNKNOWN
Acute Vascular Response To Meals Varying In Glycemic Index And Glycemic Load
Lead Sponsor:
Unity Health Toronto
Conditions:
Healthy
Eligibility:
All Genders
18-75 years
Phase:
PHASE2
Brief Summary
This study examines the effects of carbohydrate type (high- or low-Glycemic Index (GI)) and amount (high- or low-Glycemic Load (GL)) have on blood glucose levels, blood pressure and arterial stiffness...
Eligibility Criteria
Inclusion
- healthy
- age 18 - 75 years
- BMI 18 - 25 kg/m2
- brachial systolic blood pressure \< 140 mmHg
- brachial diastolic blood pressure \< 90 mmHg
Exclusion
- primary hypertension
- diabetes
- allergy or sensitivity to any foods to be used in the study
- gastrointestinal disorders
- chronic kidney disease
- liver disease
- hepatitis
- estrogen-sensitive cancer
- heavy alcohol use
- sleep apnea
- bleeding disorders
- planned surgery (within time frame of study)
- angina
- Congestive Heart Failure
- coronary revascularization
- peripheral vascular disease and/or coronary/cerebrovascular events within the previous 6 months
- positive HIV diagnosis
- prescription of anti-depressants, anti-hypertensives, anti-coagulant medications, diuretics, sympathomimetics, herbal therapies, vitamin or K supplementation, medication affecting NO synthesis
- chronic use or prescription of NSAIDs
- women of childbearing potential must not be pregnant or breastfeeding
Key Trial Info
Start Date :
August 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 1 2013
Estimated Enrollment :
21 Patients enrolled
Trial Details
Trial ID
NCT01883700
Start Date
August 1 2010
End Date
September 1 2013
Last Update
June 21 2013
Active Locations (1)
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1
Risk Factor Modification Centre, St. Michael's Hospital
Toronto, Ontario, Canada, M5B 1W8