Status:
COMPLETED
Effect of Long-term Oxygen Therapy on Exercise Capacity and Quality of Life in Patients With Pulmonary Arterial and Chronic Thromboembolic Pulmonary Hypertension
Lead Sponsor:
University of Zurich
Conditions:
Pulmonary Arterial and Chronic Thromboembolic Pulmonary Hypertension
Eligibility:
All Genders
16-85 years
Phase:
PHASE3
Brief Summary
In this randomized-controlled, cross-over trial the investigators test the effect of long-term oxygen therapy (\> 16h/day) given for 5 weeks with a wash-out period between phases of 2 weeks on exercis...
Eligibility Criteria
Inclusion
- Inclusion criteria:
- \- Adult patients with established diagnosis of pulmonary arterial or chronic thromboembolic pulmonary hypertension (class I and IV according to the latest WHO classification scheme of Dana Point 2008) on optimized medical therapy and in stable condition for at least 4 weeks, who desaturate in the 6 minute walking test by =4% to values \<92%.
- Exclusion criteria:
- Patients in unstable conditions requiring frequent therapeutic adaption
- pregnant women
- patients with pulmonary venous hypertension due to left heart diseases
- patients with relevant concomitant lung disease and severe daytime hypoxemia
Exclusion
Key Trial Info
Start Date :
May 1 2013
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2017
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT01884012
Start Date
May 1 2013
End Date
March 1 2017
Last Update
May 5 2017
Active Locations (1)
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1
University Hospital Zurich, Division of Pneumology
Zurich, Canton of Zurich, Switzerland, 8091