Status:

COMPLETED

Study of Gene Expression Profiling and Immunological Mechanism Affects the Response of Immunotherapy

Lead Sponsor:

Capital Medical University

Conditions:

Malignant Tumor

Eligibility:

All Genders

18-80 years

Brief Summary

To investigate gene expression profile and immunological associated analysis relating to immunotherapy response of patients with malignant tumor presenting malignant cavity effusion after DC-CIK immun...

Detailed Description

1. The patients with malignant cavity effusion are treated with dendritic cells (DC) plus cytokine induced killer cells (CIK) locally. 2. Malignant cavity effusion from cancer patients is obtained thr...

Eligibility Criteria

Inclusion

  • Histologically confirmed with malignant tumor and malignant cavity effusion.
  • An Eastern Cooperative Oncology Group(ECOG)performance status of 0-2.
  • Normal cardiac, hepatic, renal and bone marrow functions.
  • Life expectancy \>3 months.
  • Not receive other anti-tumor treatment.
  • Not receive chemotherapy in pleural and abdominal cavity.

Exclusion

  • Previous history of other malignancies.
  • Serious or uncontrolled concurrent medical illness.

Key Trial Info

Start Date :

March 1 2013

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

May 1 2023

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT01884168

Start Date

March 1 2013

End Date

May 1 2023

Last Update

February 7 2024

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Capital Medical University Cancer Center/Beijing Shijitan Hospital

Beijing, Beijing Municipality, China, 100038