Status:

COMPLETED

Improving Heart Health in Appalachia

Lead Sponsor:

Debra Moser

Collaborating Sponsors:

University of Kentucky Center for Excellence in Rural Health-Hazard

Conditions:

Obesity

Hypertension

Eligibility:

All Genders

21+ years

Phase:

NA

Brief Summary

Individuals in Appalachian Kentucky are vulnerable to cardiovascular disease (CVD) by virtue of having high rates of multiple CVD risk factors. There is a critical need to develop and test CVD risk re...

Eligibility Criteria

Inclusion

  • residents of eastern Appalachian Kentucky
  • do not have a primary care provider
  • at risk for CVD as reflected by having two or more of the following modifiable risk factors
  • clinical diagnosis of hypertension or taking medications diagnosed for hypertension or found to be hypertensive on screening;
  • clinical diagnosis of hyperlipidemia or taking medication for treating abnormal lipid levels, or any lipid abnormality found on screening that indicates hyperlipidemia;
  • diagnosis of type 2 diabetes or HgA1c \> 7% found on screening;
  • overweight or obese (body mass index ≥ 25 kg/m2);
  • waist circumference \> 40 inches in men or \> 35 inches in women;
  • clinical diagnosis of depression, on medications for depression or found to have depressive symptoms (score of \> 9 on the Patient Health Questionnaire-9) by baseline screening;
  • sedentary lifestyle meaning that the individual does not engage in at least 30 minutes of moderate activity for at least 4 days per week

Exclusion

  • known coronary artery disease, cerebrovascular disease, history of acute coronary syndrome or peripheral arterial disease;
  • taking medications (e.g., protease inhibitors) that interfere with lipid metabolism;
  • cognitive impairment that precludes an individual from understanding the consent process, answering questionnaires, or participating in the intervention;
  • chronic drug abuse;
  • end-stage renal or liver or pulmonary disease;
  • current active cancer (i.e., undergoing active treatment for cancer) other than isolated skin cancer treatable by simple excision;
  • gastrointestinal disease that requires special diets (e.g., Crohn's disease; celiac disease)

Key Trial Info

Start Date :

August 1 2013

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 31 2016

Estimated Enrollment :

330 Patients enrolled

Trial Details

Trial ID

NCT01884246

Start Date

August 1 2013

End Date

December 31 2016

Last Update

March 10 2017

Active Locations (1)

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Page 1 of 1 (1 locations)

1

University of Kentucky

Lexington, Kentucky, United States, 40535