Status:

COMPLETED

Vitamin D Supplementation for Bipolar Depression

Lead Sponsor:

University of Massachusetts, Worcester

Conditions:

Bipolar Disorder

Bipolar Depression

Eligibility:

All Genders

18-75 years

Phase:

NA

Brief Summary

The purpose of this study is to whether vitamin d supplementation in those with low levels may reduce depression symptoms in people experiencing bipolar depression.

Eligibility Criteria

Inclusion

  • Adults \>18years old
  • Bipolar disorder (I,II or NOS),
  • MADRS Score\>7 (mild),
  • 25(OH)D level \<30ng/ml (insufficient).
  • able to take the prescribed vitamin D by mouth

Exclusion

  • Systemic diseases such as:
  • liver and kidney diseases,
  • known parathyroid disorder,
  • disorders of vitamin D metabolism,
  • taking vitamin D replacement therapy,
  • fat digestion disorder,
  • diabetes mellitus,
  • gi surgery
  • If the serum calcium in the range 2.50-2.55 mmol L, inclusion required a serum PTH below 5.0 pmol L-acute psychiatric urgency:
  • active suicidality,
  • acute psychosis,
  • active substance use\<6mo or
  • pregnant or nursing females

Key Trial Info

Start Date :

June 1 2013

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 1 2015

Estimated Enrollment :

33 Patients enrolled

Trial Details

Trial ID

NCT01884844

Start Date

June 1 2013

End Date

August 1 2015

Last Update

June 19 2018

Active Locations (2)

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Page 1 of 1 (2 locations)

1

University of Massachusettes

Worcester, Massachusetts, United States, 01604

2

University of Massachusetts School of Medicine

Worcester, Massachusetts, United States, 01605

Vitamin D Supplementation for Bipolar Depression | DecenTrialz