Status:

COMPLETED

Ibuprofen Supplementation After Resistance Training and Its Effects on Bone in Older Women

Lead Sponsor:

University of Saskatchewan

Collaborating Sponsors:

Canadian Institutes of Health Research (CIHR)

Conditions:

Sarcopenia

Osteoporosis

Eligibility:

FEMALE

65+ years

Phase:

NA

Brief Summary

Inflammation increases with aging and is implicated in the reduction of bone mass, muscle mass, and strength. Resistance training is safe and effective for increasing muscle mass and strength in older...

Detailed Description

The aim of our study is to create new evidence about the effectiveness and safety of non-steroid anti-inflammatory supplementation (i.e. ibuprofen) combined with exercise to influence positively bone ...

Eligibility Criteria

Inclusion

  • women \>65yrs

Exclusion

  • high risk of fracture
  • use of bisphosphonates, hormone replacement therapy, selective estrogen receptor modulators, PTH, or calcitonin within the past 12 months
  • taking medications that affect bone mineral metabolism
  • have diseases that are known to affect bone mineral metabolism
  • have severe osteoarthritis
  • currently a smoker
  • currently participating in moderate-vigorous resistance-exercise training more than once per week

Key Trial Info

Start Date :

April 1 2013

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 1 2014

Estimated Enrollment :

90 Patients enrolled

Trial Details

Trial ID

NCT01886196

Start Date

April 1 2013

End Date

July 1 2014

Last Update

May 5 2017

Active Locations (1)

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College of Kinesiology

Saskatoon, Saskatchewan, Canada, S7N5B2